I do not know what changes are to come, but while I expect there to be a few I don't think they'll be very significant.
Think about how it must have been during the polio pandemic or the first influenza outbreak, medicine was not as advanced as it was now and a lot of the technology and conveniences we have today were not present.
Information in the palm of your hand, food delivery everywhere,grocery and supply delivery available within hours.
Major changes came when those eye openers wiped through the nation, at this point I'm not sure there's much that can change unless people change their way of life in a major way which we all know nobody wants to do.